Gastrin cell function in familial multiple endocrine neoplasia type I.
نویسندگان
چکیده
منابع مشابه
Gastrin cell function in familial multiple endocrine neoplasia type I.
Recent studies have suggested that patients with multiple endocrine neoplasia type I (MEN I) may have abnormal serum gastrin secretion in the absence of gastrin producing tumours. G-(gastrin) cell function by three provocation tests in 20 patients with hyperparathyroidism from six MEN I-families were studied: each patient was an obligate carrier of the MEN I-gene. The serum gastrin response to ...
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An adult woman 43 years old, with Multiple Endocrine Neoplasia type 2A (MEN2A). Clinical diagnosis of MEN2A was made based on the chief complaints of abdominal pain and a lump in the front left side area of neck accompanied with weight loss, from laboratory examination revealed an increased level of plasma levels of calcitonin levels with the result of 6359 pg/ml and 24 hours metanephrine urine...
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The term Multiple Endocrine Neoplasia Type 1 (MEN 1) is applied to familial as well as to sporadic cases (Brandi et al., 1987). -The familial form, known Familial Multiple Endocrine Neoplzzia Type 1 (FMEN 1) is an autosomal dominant disorder with hyperfunction of the parathyroids, the pancreatic islets, and the anterior pituitary. The sporadic cases are characterized by endocrine tumors in two ...
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Combined clinical and laboratory investigations of MEN-1 have resulted in an increased understanding of this disorder, which may be inherited as an autosomal dominant condition. Defining the features of each disease manifestation in MEN-1 has improved patient management and treatment and has facilitated a screening protocol. Application of the techniques of molecular biology has enabled the ide...
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Multiple endocrine neoplasia-1 (MEN-1) is an autosomal dominant inherited syndrome that occurs due to inactivating mutations of the MEN1 gene locus, coding for a tumor-suppressor protein, menin. The components of MEN-1 are hyperparathyroidism due to multiple parathyroid adenomas, pancreatic neuroendocrine tumors, and pituitary adenomas, in addition to some less common neoplastic manifestations....
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ژورنال
عنوان ژورنال: Gut
سال: 1988
ISSN: 0017-5749
DOI: 10.1136/gut.29.10.1358